Cytopathology in Oncology

Cancer Cytopathology
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May —The genomic landscape of non-small cell lung carcinoma is evolving constantly with the discovery of a growing number of molecular alterations and associated targeted therapies that have an impact on patient care.

The CAP, International Association for the Study of Lung Cancer, and Association for Molecular Pathology issued a guideline in to provide a road map for molecular testing to select patients for treatment with targeted tyrosine kinase inhibitors. It provides recommendations that affect cytopathology and the role of the cytopathologist in providing clinically relevant genomic information for the treatment of patients with NSCLC.

The main updated recommendations pertaining to cytologic specimens are summarized in Table 1.


Afrogheh Syed Z. Learn about clinical trials at MD Anderson and search our database for open studies. Readers will also explore detailed descriptions of the morphologic spectrum of the neoplasms including different terminologies , as well as their immunocytohistochemical properties, associated ultrastructural findings, secretory products, and their association with many hereditary syndromes. Kim , Peggy P. April

This is a significant update from the guideline in which cell blocks were recommended as a preferred substrate for testing. The updated guideline opens the door to better utilization of non-cell block i. Several studies have indicated the limitations of restricting molecular testing to cell blocks alone, including a lack of on-site assessment for adequacy, variable cellularity, and suboptimal nucleic acid quality subject to formalin fixation and paraffin embedding.


Learn about our graduate medical education residency and fellowship opportunities. The B-Cell Lymphoma Moon Shot is revolutionizing the conventional medical research approach to rapidly translate findings into patient treatment options and develop personalized therapeutic strategies. The objective of this one-year fellowship is to provide a concentrated experience in diagnostic cytopathology including the interpretation of both aspiration and exfoliative cytologies and the performance of superficial needle aspirations. The fellow participates in a number of teaching cytology conferences can attend a variety of surgical pathology conferences, and must ready a research project for publication under staff supervision.

People of MSK

Supplementation of the gynecologic cytology portion of the program is achieved through a two-week rotation with the Methodist Hospital and a mandatory slide gynecologic cytology study set review. Immediate assessment of specimen adequacy is made for all aspirations superficial and deep CT, ultrasound and endoscopic ultrasound.

Selected specimens primarily urine are evaluated for DNA content image analysis or chromosomal abnormalities FISH within the cytology laboratory. To be considered for an interview, your file must be complete before July 15 24 months prior to the start of the training year , which begins July 1.

John Stewart, M. Requests for verification should be sent to ybanuelos mdanderson.

Cytology tests on body fluids

In recent decades, cytopathology has assumed an increasing role in the primary diagnosis of mass lesions owing to its ability to deliver rapid, non-invasive, and. Cancer Cytopathology, a journal of the American Cancer Society, publishes original research and other articles of interest to cytopathology, cytology, and.

MD Anderson Cancer Center is committed to encouraging good health and staying true to our mission to end cancer. If you are applying for a GME fellowship or residency program starting on or after July 1, , please be advised that MD Anderson will have instituted a tobacco-free hiring process as part of its efforts to achieve these goals.

Cytopathology Laboratory

If you are offered an appointment, you will be subject to a Pre-Employment Drug Screen for tobacco compounds in compliance with applicable state laws. In the last decade, the department has made significant progress, especially in the fields of cervical cancer diagnostics, immunocytochemistry and flow cytometry diagnostics of lymphoma and leukaemia. Hybrid Capture 2 in With the development of new antibodies, immunocytochemistry became an important additional method for classifying malignant tumours and diagnosing cancer of unknown primary.

In , they joined the iBFM international consortium and started to provide flow cytometry diagnostics of minimal disease residues in children with acute lymphoblastic leukaemia for the whole Slovenia. Two years later, they received the first international certificate for performing these diagnostics.

Types and Number of Appointments